Ryman Gun Dog wrote:Gentlemen,
I do not use Ivormec any more, I have been using an extrernal product called Advocate for many years now. I believe its better for my dogs, and it works very very well
on just about every kind of paracite known to man. I also use Adams spray.
kninebirddog wrote:I do not see where it says Kills Heartworm as that is the prime reason for giving Ivermectin
Pet Owner Resources | Canine Heartworm
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Canine Heartworm AnimationCanine Heartworm Disease
* Canine Heartworm Disease
* Clinical Signs
* Canine Brochure
Canine Heartworm Disease
Dogs are considered the definitive host for heartworms ( Dirofilaria immitis). However, heartworms may infect more than 30 species of animals (e.g., coyotes, foxes, wolves and other wild canids, domestic cats and wild felids, ferrets, sea lions, etc.) and humans as well. When a mosquito carrying infective heartworm larvae bites a dog and transmits the infection, the larvae grow, develop and migrate in the body over a period of several months to become sexually mature male and female worms. These reside in the heart, lungs and associated blood vessels. As mature adults, the worms mate and the females release their offspring (microfilariae), pronounced: (micro-fil-ar-ee-a), into the blood stream.
Offspring can be detected in the blood (pre-patent period) about six to seven months after the infective larvae from the mosquito enter the dog. The male heartworms (four to six inches in length) and the females (10-12 inches) become fully grown about one year after infection, and their life span in dogs appears to average up to five to seven years.
Elimination of Microfilariae
The most effective drugs for this purpose are the macrocyclic lactone (ML) anthelmintics, i.e.,milbemycin oxime, selamectin, moxidectin and ivermectin. These drugs are the active ingredients in commonly used heartworm preventives. Although their usage as microfilaricides has not been approved by the FDA, they are widely used by veterinarians as there are no approved microfilaricidal drugs currently available. It is recommended that microfilariae positive dogs being treated with these macrocyclic lactones be hospitalized for at least eight hours following treatment for observation of possible adverse reactions, including those resulting from rapid death of the microfilariae.
Circulating microfilariae usually can be eliminated within a few weeks by the administration of the ML-type drugs mentioned above. Today however, the most widely used microfilaricidal treatment is to simply administer ML preventives as usual, and the microfilariae will be cleared slowly over a period of about six to nine months.
Confirmation of Adulticide Efficacy
The goal of adulticide treatment is the elimination of all adult heartworms. However, clinical improvement in dogs treated for heartworm infection is possible without completely eliminating the adult heartworms. Heartworm antigen testing is the most reliable method of confirming the efficacy of adulticide therapy. If all the adult worms have been destroyed or very few survive, heartworm antigen should be undetectable after six months post-adulticide. Dogs that remain antigen positive at that time could be considered a potential candidate for repeat treatment with an adulticide only after a full review of each case. In some cases, an alternative is to not retreat with the arsenical but to continue with a preventive such as ivermectin which will gradually eliminate the remaining worms.
While treatment of canine heartworm disease is usually successful, prevention of the disease is much safer and more economical. There are a variety of options for preventing heartworm infection, including daily and monthly tablets and chewables, monthly topicals and a six-month injectable product. These products are extremely effective and when administered properly on a timely schedule, heartworm infection can be prevented.
The American Heartworm Society is now recommending year-round prevention, even in seasonal areas. One reason for this is compliance – to make sure the medicine has been given properly by the pet owner. In addition, most monthly heartworm preventives have activity against intestinal parasites. Many of these same intestinal parasites that infect dogs can also infect people, with estimated infections occurring in three to six million people every year. So this added benefit of monthly deworming makes great sense.
Before starting a preventive program, all dogs that could possibly be infected with mature heartworms should be tested.
Macrocyclic Lactone (ML)
Macrocyclic lactones are highly effective parasiticides used in preventing heartworm infections. Their primary benefits lie in their safety and ease of administration of once- monthly doses. Each of the macrocyclic lactones can have additional intestinal parasite or external parasite activity, which could be the determining factor that a veterinarian uses to recommend a particular product for a certain region or an individual situation.
Ivermectin (Heartgard® & Heartgard® Plus by Merial, Iverhart® Plus & Iverhart MAX™ by Virbac and Tri-Heart® Plus by Schering-Plough) was the first in this family of drugs to be approved for preventing heartworm infection. An infection with larvae as long as two months prior to the initiation of ivermectin treatment will be blocked from development.
Milbemycin oxime (Interceptor® & Sentinel® by Novartis) has benefits, which are similar to ivermectin.
Selamectin (Revolution® by Pfizer) is applied topically to prevent heartworm disease.
Moxidectin (Advantage Multi™ by Bayer) is available in a topical formulation, in combination with a flea control product, imidacloprid. Moxidectin is also available as a six-month injectable product for dogs (ProHeart®6 (moxidectin) Sustained Release Injectable for Dogs, by Fort Dodge Animal Health).
Ron R wrote:Merle wrote:For those using ivomec I am curious to know how many of you use it all year long
I give 1cc through the summer months and 1/2 cc through fall, winter, and spring.
MOOSE wrote:I have had to put 3 dogs through the treatment for Heartworms that were rescues and positive.
A Heartworm (Adult) only has a certain life span. So when using Ivermectin it is killing off the eggs/larva that is laid by the adults (if they are present) or if a bug bites the dog and puts eggs/larva in the dogs system it kills those as well.
If a dog IS Heartworm Positive you CAN treat it with Ivomectin only but this take A LOT of time as you may have adult Heartworms that are different ages. But EVENTUALLY ALL the adult HW would die off. This being said if it is a severe case of HW this would NOT be a good option as it would be too slow and the HW could kill the dog still. To only way to kill off the adult HW before it reaches the phase where it would die naturally is through using Immiticide, a drug containing arsenic. It is very expensive and depending on how severe the HW it can be VERY dangerous too. Prevention is KEY with HW.
duckn66 wrote:I may have missed this and I'm sure I did but is the Ivermectin treatment a once a month deal like the pills? I've used it for treatment of Red Mange but never for heartworm prevent.
Also I see guys using paste, or putting it on bread or peanut butter. Whats wrong with just squirting the 1 percent injectable directly on their dog food?
Rick Hall wrote:Been using Ivomec given orally at the dosage Ezzy posted (or a bit higher) for years, and our fleas must be tougher than his. Try not to leave a tick on a dog long enough to know if its been poisoned, so I can't speak as confidently about whether it affects them.
ezzy333 wrote:o__o wrote:So you do get ticks?ezzy333 wrote:All I know about Ivomec usage is that I do not have any fleas and rarely a tick on the dogs since I have been using it.
You get ticks with any preventative. They get on the dog and bite but then die if the preventative is working. Not much else you can do about them if you have them around. Don't know of any that will keep all of them off of the dog or you though some things do help.
All the information you need is in this book. I have it, and yes - that is where the dosage regimen came from: http://www.oldcountryvet.com/
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