Novartis Suspends Production of Several Products

[Cajun Casey]

Interceptor, Deramaxx and Clomicalm, among others.

http://blog.vetdepot.com/novartis-suspe ... 5.facebook

[bossman]

Thanks for the "heads up". Very interesting

[Cajun Casey]

Another tidbit - the active ingredient in Interceptor is combined by Dow Elanco with spinosad to make Trifexis. Spinosad has had bad reports when used in pregnant bitches and cannot be used in pups under 14 weeks.

[dog dr]

Another tidbit - the active ingredient in Interceptor is combined by Dow Elanco with spinosad to make Trifexis. Spinosad has had bad reports when used in pregnant bitches and cannot be used in pups under 14 weeks.

"Clinical findings in pups of the treated groups were comparable to the control group except for one 1X group pup that was smaller and less coordinated than its littermates and had tremors when excited. The relationship between spinosad and milbemycin oxime treatment and the 1X and 3X dogs that did not become pregnant, the specific pup malformations and the unthrifty 1X group pup are unknown. The incidence of cleft palate is not unexpected based on the historical data collected at the breeding site. "

I dont know, doesnt sound all that bad to me. If you read the whole article you find out that there were only about 3 or 4 total pups that showed any defects at all, and i think at least 2 of those were in the control group.

[ezzy333]

Another tidbit - the active ingredient in Interceptor is combined by Dow Elanco with spinosad to make Trifexis. Spinosad has had bad reports when used in pregnant bitches and cannot be used in pups under 14 weeks.

"Clinical findings in pups of the treated groups were comparable to the control group except for one 1X group pup that was smaller and less coordinated than its littermates and had tremors when excited. The relationship between spinosad and milbemycin oxime treatment and the 1X and 3X dogs that did not become pregnant, the specific pup malformations and the unthrifty 1X group pup are unknown. The incidence of cleft palate is not unexpected based on the historical data collected at the breeding site. "

I dont know, doesnt sound all that bad to me. If you read the whole article you find out that there were only about 3 or 4 total pups that showed any defects at all, and i think at least 2 of those were in the control group.

Thank you for getting the correct information out where everyone can see it. We continue to have the age old problem of someone picking up a piece of information that doesn't understand it but still putting it out as fact and then it gets spread from there.

Ezzy

[Cajun Casey]

Until spinosad's labled safe, we will recommend alternatives for the few clients with breeding females. Trifexis is the product we recommend in most cases because it commits the client on flea protection.

[VizslaGirl]

We love the concept of Trifexis, but have had a high rate of vomiting with it (even when given with food). Have you seen that frequently, Cajun? We move a fair amount of Sentinel/Interceptor' so hopefully Novartis gets their act together soon!

[crazyboy]

Just came on to post the same link, I see someone beat me to it.

[Cajun Casey]

We love the concept of Trifexis, but have had a high rate of vomiting with it (even when given with food). Have you seen that frequently, Cajun? We move a fair amount of Sentinel/Interceptor' so hopefully Novartis gets their act together soon!

Haven't had any issues that I know of and our clients are pretty vocal about problems. My unit vet suggests giving meds with a small evening meal, so timing the dose to when the animal is calmer may help. What's got my DVM folks riled up is how this reflects on their professional integrity. Novartis has kind of cut us loose in rough seas.

[VizslaGirl]

Yep - it doesnt 't make anyone look good.

I'll recommend giving Trifexis specifically with the PM meal - thanks for the idea!

We love the concept of Trifexis, but have had a high rate of vomiting with it (even when given with food). Have you seen that frequently, Cajun? We move a fair amount of Sentinel/Interceptor' so hopefully Novartis gets their act together soon!

Haven't had any issues that I know of and our clients are pretty vocal about problems. My unit vet suggests giving meds with a small evening meal, so timing the dose to when the animal is calmer may help. What's got my DVM folks riled up is how this reflects on their professional integrity. Novartis has kind of cut us loose in rough seas.

[dog dr]

We love the concept of Trifexis, but have had a high rate of vomiting with it (even when given with food). Have you seen that frequently, Cajun? We move a fair amount of Sentinel/Interceptor' so hopefully Novartis gets their act together soon!

I have had some success with giving it on a full stomach, as opposed to "with" the meal. might try that. interestingly enough, we dont see the vomiting issues with the Trifexis nearly like we do with Comfortis. Not sure why.