birddogger wrote:Why dilute it? Just curious...I use the paste, one click for 5o# dogs...I just push it out on my finger and rub it off on the roof of the mouth.

Charlie

If my calculations are correct, this 6.08 gram tube contains enough for 1 - 1250 pound horse at 91 micrograms (.000091) per pound that puts .11375 grams of product in the tube, or 113750 micrograms of Ivermectin. Each 'click is 50 pounds, so one click will dispense roughly 4550 micrograms of Ivermectin.

If I where to buy Heartgard, my 15 pound little Fox Terrier would get the 68 mgm tablet (although he only requires 40 micrograms at 2.72 mgms per pound). My 45 pound mix breed would get the 136 mgms tablet, although she would only require 122 mgms.

A 50 pound dog requires 136 mgms, and you are dispensing 4550 mgms with one click.

Please correct me if I am wrong on these calculations.

Please excuse me, but my O.C.D. is kicking in

I found this great recap on another site and thought I would bring it here.

DOSAGE SUMMARY: I do not recommend anything, I am just sharing my calculations to maybe help prevent a problem.

Heartgard's dosage level: 2.72 microgram (mcg) per pound of dog

A 1% solution (like Ivomec) contains 10,000 mcg in just one ml of undiluted, from the bottle, solution. For a 100 lb dog, you only need 272 mcg (.272 mg) of ivermectin ingredient and that is contained in only .0272 ml (cc) of 1% undiluted solution. Tiny amount per month folks to equal Heartgard's dosage. So the corrected chart posted by dog nut is for that level:

Dogs weight = volume of 1% undiluted solution

10 lbs = .0027 cc or ml (call it .003)

20 lbs = .0055 cc or ml

30 lbs = .0082 cc or ml

40 lbs = .011 cc or ml

50 lbs = .013 cc or ml

60 lbs = .016 cc or ml

70 lbs = .019 cc or ml

80 lbs = .022 cc or ml

90 lbs = .025 cc or ml

100 lbs = .027 cc or ml

You need a tiny syringe. But recall that 50 lbs to 100 lbs can all take the .027ml, roughly .03 ml, dose. Understand that .03cc is 3/100 of a cc. NOT 3 tenths!

All the dilutions reduce the amount of ivermectin per cc, so that you can have more liquid to more easily measure it out but still get the same total amount of ivermectin ingredient.

If others are correct, then .1 (1/10th)cc per 10 pounds is a safe max maybe. That is .01 ml per pound which delivers 100 mcg per pound. Do realize that is much much higher than the Heartgard dose of 2.72 mcg per lb. 30 times plus.

If you dilute the original 1% solution, 1 part to 9 parts other liquid (options in above thread, but not water), then you could use this diluted solution at the same 1/10 cc per 10 lbs of dog ratio but then your dog would get 10 mcg per pound. Safer likely but still above the 2.72 mcg Heartgard.